Therapeutic injections are often used to treat persistent severe pain that is not easily managed by pain medications, lifestyle modifications or physical therapy. They are often used in place of major surgery to avoid or reduce the use of prescription painkillers. Therapeutic injections serve as a clinical procedure to treat orofacial pain, acting as both a diagnostic tool and a means to predict treatment outcomes. They can be helpful in avoiding invasive surgery and may include anaesthetic or anti-inflammatory medications targeted toward specific nerves or nerve groups associated with pain. By precisely targeting the source of discomfort, therapeutic injections provide both immediate relief and long-term management of orofacial pain, ultimately enhancing the overall quality of life for patients.